Think Neuro

Think Neuro Mini: Understanding Insulin Resistance with Dr. Jennifer Bramen

Episode Summary

It’s important to understand the connection between carbohydrates and Alzheimer's disease. Brain cells depend on insulin to use glucose effectively. When insulin resistance sets in, as it often does with older age and AD, it can lead to cognitive decline. Both AD and type 2 diabetes share common mechanisms, including impaired insulin signaling. Lowering blood sugar and insulin levels could also help clear harmful Aβ peptides (amyloid buildup) that contribute to AD. Eating fewer carbohydrates results in lower overall blood sugar.

Episode Notes

It’s important to understand the connection between carbohydrates and Alzheimer's disease. Brain cells depend on insulin to use glucose effectively. When insulin resistance sets in, as it often does with older age and AD, it can lead to cognitive decline. Both AD and type 2 diabetes share common mechanisms, including impaired insulin signaling. Lowering blood sugar and insulin levels could also help clear harmful Aβ peptides (amyloid buildup) that contribute to AD. Eating fewer carbohydrates results in lower overall blood sugar.